'Benign' hypertensive nephrosclerosis

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"Benign" hypertensive nephrosclerosis.

BACKGROUND Whether benign hypertensive nephrosclerosis (BHN) causes end-stage renal failure (ESRF) is controversial. One reason for this is the lack of biopsy evidence confirming the clinical diagnosis in most cases. AIM To investigate whether biopsy-proven BHN leads to ESRF. DESIGN Retrospective analysis. METHODS We analysed all cases of biopsy-proven BHN from a single centre over a peri...

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Renal ablation acutely transforms 'benign' hypertension to 'malignant' nephrosclerosis in hypertensive rats.

The present studies examine the consequences of the hemodynamic changes associated with approximately 5/6 renal ablation in the spontaneously hypertensive rat (SHR), a strain that normally does not exhibit evidence of vascular and/or glomerular injury until late in life despite significant hypertension. Control SHR with intact renal mass demonstrated normal renal autoregulation and an absence o...

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Clinical prognostic factors in biopsy-proven benign nephrosclerosis.

BACKGROUND Hypertensive renal damage has become one of the most important causes of end-stage renal failure (ESRF) in Western countries. Affected patients rarely have a kidney biopsy and their diagnoses therefore remain uncertain. The objective of the present study was to examine patients suspected of renal glomerular disease, which at biopsy proved to have isolated benign nephrosclerosis. We w...

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ACE inhibitors and appearance of renal events in hypertensive nephrosclerosis.

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Hypertensive nephrosclerosis as a relevant cause of chronic renal failure.

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ژورنال

عنوان ژورنال: QJM

سال: 2006

ISSN: 1460-2725,1460-2393

DOI: 10.1093/qjmed/hcl139